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Special Issue "New Therapeutic Approaches in Gastrointestinal Cancers: A Step Toward the Personalized Medicine"

Special Issue Information

Dear Colleague

Gastrointestinal cancers are one of most common chronic diseases and are among the top three causes of mortality in the world. Despite extensive improvements in surgery, chemotherapy, radiotherapy and target therapy over the last decades, the outlook for patients remains miserable, with short survival in advanced cancer stages and recurrence. MicroRNAs (miRNAs) are evolutionary conserved, short (~22 nucleotides in length), single-stranded RNA molecules that attributed to the big family of small non-coding RNAs. MiRNAs contribute in the tumorgenesis as either tumor suppressors (oncosuppressor) or oncogenes (oncomiR), therewith modulating the derepression of target miRNA. micro-RNAs can be circulated in body fluid, suggesting their values as noninvasive predictor marker of cancer diagnosis, classification, prognosis, and response to treatment. The thematic issue provide the readers working in basic biomedical sciences as well as clinicians a comprehensive overview on diagnostic, prognostic significance and targeting miRNAs and New therapeutic approaches including nanomedince in gastrointestinal cancers.

Dr. Amir Avan
Dr. Elisa Giovannetti
Guest Editors

Manuscript Submission Information